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lnrJ [2019-07-25 09:42:14]
two-component sensor kinase, involved in resistance to linearmycin
function
involved in resistance to linearmycin
product
two-component sensor kinase
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.2|Protein kinases][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.1|Two-component sensor kinase][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.4|Phosphorylation on a His residue]Gene
Coordinates
903,811 905,013
The protein
Catalyzed reaction/ biological activity
autophosphorylation, phosphorylation of [protein|387EF370CE24F7A3C20789A57329A02EBED46F53|LnrK][SW|Domains]
5 transmembrane segmentsModification
autophosphorylation on a His residue[SW|Localization]
cell membrane (according to UniProt)Expression and Regulation
Operons
genes
[gene|03AEADB134F1CAD8BBB3E1F625D597EBA1FDA30B|lnrJ]-[gene|387EF370CE24F7A3C20789A57329A02EBED46F53|lnrK]
description
[Pubmed|8973323]
view in new tabBiological materials
Mutant
BKE08290 ([gene|03AEADB134F1CAD8BBB3E1F625D597EBA1FDA30B|lnrJ]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE08290 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGCTCATCACTCCCGATA, downstream forward: _UP4_GTGCAGCAAAAGGAGAGTTTBKK08290 ([gene|03AEADB134F1CAD8BBB3E1F625D597EBA1FDA30B|lnrJ]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK08290 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGCTCATCACTCCCGATA, downstream forward: _UP4_GTGCAGCAAAAGGAGAGTTTReferences
10094672,8973323,26647299,28461449